Isolation of Streptomycin-producing Strains of Streptomyces griseus

Isolation of streptomycin-producing strains of Streptomyces griseus.

Variations in Strains of Streptomyces griseus Isolated from a Degenerating Streptomycin-Producing Culture.

Streptomycin-resistant strains were isolated from a degenerated streptomycin-producing culture of Streptomyces griseus. From 250 resistant strains, 3 low, 2 intermediate, and 2 high potency strains were selected; these were compared in their morphological, cultural, physiological, and streptomycin-producing properties. Though no definite correlation between streptomycin production and the other...

Isolation and characterization of a phage active against streptomyces griseus

Enzymatic phosphorylation of streptomycin by extracts of streptomycin-producing strains of Streptomyces.

Extracts of post-exponential phase mycelia of Streptomyces bikiniensis ATCC 11062, and other streptomycin-producers, catalyze phosphorylation of streptomycin and dihydrostreptomycin with adenosine-5'-triphosphate. The phosphate is esterified with an -OH group of the streptidine moiety. It is suggested that O-phosphoryl-streptomycin might serve as an intracellular precursor of extracellular stre...

Production of streptomycin from chitin using Streptomyces griseus in bioreactors

Streptomyces griseus was cultured in three different bioreactors in a medium containing chitin flakes. When a conventional bioreactor stirred by two sets of Rushton impellers and operated at high speed was used, the yield of streptomycin (3.1 mg/l) was the highest observed and occurred at approximately 500 hours. Cultivation of S. griseus in a bioreactor stirred at low speed by a U-shaped paddl...